The Straight Up Peptides newsletter

New trial results on GLP-1 medicines, retatrutide, and the peptides people talk about, explained in plain language with the citation next to every number.

Launching soon. Until the first issue goes out, every new write-up lands on the articles page first.

What each issue covers

• One new trial, unpacked. What it measured, who was in it (people or animals), how big it was, and what it does not tell you.
• What changed on the rules. Approval, prescription, and compounding news, broken out for the US and Canada.
• One myth, checked. A claim making the rounds online, held up against the published evidence.

Every issue follows the same rules as the site: research information, not medical advice. No dosing protocols, no cycles, and no supplier picks.

Read while you wait

• Peptide research glossary: the plain-English starting point.
• Semaglutide vs tirzepatide: what the head-to-head trial found.
• Retatrutide TRIUMPH trial results: the published Phase 3 numbers.